A reduce and replace strategy for suppressing vector-borne diseases: insights from a stochastic, spatial model.

Two basic strategies have been proposed for using transgenic Aedes aegypti mosquitoes to decrease dengue virus transmission: population reduction and population replacement. Here we model releases of a strain of Ae. aegypti carrying both a gene causing conditional adult female mortality and a gene b...

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Bibliographic Details
Main Authors: Kenichi W Okamoto, Michael A Robert, Alun L Lloyd, Fred Gould
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3869666?pdf=render