Systematic inference and comparison of multi-scale chromatin sub-compartments connects spatial organization to cell phenotypes

Systematic inference and comparison of multi-scale chromatin sub-compartments connects spatial organization to cell phenotypes

Computational algorithms to infer chromatin sub-compartments and compartment domains require high-resolution Hi-C maps. Here the authors present Calder, an algorithm that can infer sub-compartments and compartment domains with variable resolution Hi-C data, and they apply it to more than a hundred H...

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Bibliographic Details
Main Authors: Yuanlong Liu, Luca Nanni, Stephanie Sungalee, Marie Zufferey, Daniele Tavernari, Marco Mina, Stefano Ceri, Elisa Oricchio, Giovanni Ciriello
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-22666-3

Internet

https://doi.org/10.1038/s41467-021-22666-3

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