Elevated IgG Responses in Infants Are Associated With Reduced Prevalence of Mycobacterium tuberculosis Infection

Elevated IgG Responses in Infants Are Associated With Reduced Prevalence of Mycobacterium tuberculosis Infection

BackgroundIt is unclear whether antibodies can prevent Mycobacterium tuberculosis (Mtb) infection. In this study, we examined the relationship between total plasma IgG levels, IgG elicited by childhood vaccines and soil-transmitted helminths, and Mtb infection prevalence, defined by positive QuantiF...

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Bibliographic Details
Main Authors: Erin Logan, Angelique Kany Kany Luabeya, Humphrey Mulenga, Dunja Mrdjen, Cynthia Ontong, Adam F. Cunningham, Michele Tameris, Helen McShane, Thomas J. Scriba, William G. C. Horsnell, Mark Hatherill
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Immunology
Subjects:
Mycobacterium tuberculosis infection
antibody
enzyme-linked immunosorbent assay
Bacille Calmette-Guérin
vaccine
helminth
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01529/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01529/full

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