Allele frequency misspecification: effect on power and Type I error of model-dependent linkage analysis of quantitative traits under random ascertainment
<p>Abstract</p> <p>Background</p> <p>Studies of model-based linkage analysis show that trait or marker model misspecification leads to decreasing power or increasing Type I error rate. An increase in Type I error rate is seen when marker related parameters (e.g., allele...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2006-04-01
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Series: | BMC Genetics |
Online Access: | http://www.biomedcentral.com/1471-2156/7/21 |