Evolution of Salmonella enterica virulence via point mutations in the fimbrial adhesin.

Whereas the majority of pathogenic Salmonella serovars are capable of infecting many different animal species, typically producing a self-limited gastroenteritis, serovars with narrow host-specificity exhibit increased virulence and their infections frequently result in fatal systemic diseases. In o...

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Bibliographic Details
Main Authors: Dagmara I Kisiela, Sujay Chattopadhyay, Stephen J Libby, Joyce E Karlinsey, Ferric C Fang, Veronika Tchesnokova, Jeremy J Kramer, Viktoriya Beskhlebnaya, Mansour Samadpour, Krzysztof Grzymajlo, Maciej Ugorski, Emily W Lankau, Roderick I Mackie, Steven Clegg, Evgeni V Sokurenko
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3369946?pdf=render