The prognostic value of epigenetic silencing of p16 gene in NSCLC patients: a systematic review and meta-analysis.

BACKGROUND: The prognostic significance of p16 promoter hypermethylation in patients with non-small cell lung cancer (NSCLC) is still controversial. This analysis presents pooled estimates of the association to better elucidate whether p16 methylation has a prognostic role in NSCLC. METHODS: Relevan...

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Bibliographic Details
Main Authors: Zhang Lou-Qian, Yin Rong, Li Ming, Yang Xin, Jiang Feng, Xu Lin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3555860?pdf=render