The Hippo–YAP Signaling as Guardian in the Pool of Intestinal Stem Cells

Despite endogenous insults such as mechanical stress and danger signals derived from the microbiome, the intestine can maintain its homeostatic condition through continuous self-renewal of the crypt–villus axis. This extraordinarily rapid turnover of intestinal epithelium, known to be 3 to 5 days, c...

Full description

Bibliographic Details
Main Authors: Yoojin Seo, So-Yeon Park, Hyung-Sik Kim, Jeong-Seok Nam
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Biomedicines
Subjects:
YAP
Online Access:https://www.mdpi.com/2227-9059/8/12/560