Evaluation of the Reactogenicity, Safety and Immunogenicity of the Domestic Influenza Inactivated Split FLU-M Vaccine in Immunization Adults aged 18–60 Years

This article presents the results of a simple, blind, randomized, placebo-controlled, single-center, prospective research of the reactogenicity, safety, and immunogenicity of the domestic influenza inactivated split vaccine «Flu-M» in immunization of the adult population of 18–60 years old. Low reac...

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Main Authors:	I. V. Fel'dblyum, S. D. Novgorodova, G. M. Ignat'ev, S. O. Golodnova, V. P. Trukhin, S. Ya Melnikov
Format:	Article
Language:	Russian
Published:	Numikom LLC 2018-02-01
Series:	Эпидемиология и вакцинопрофилактика
Subjects:	vaccine against influenza flu-m adult population of 18–60 years old safety reactogenicity immunogenicity
Online Access:	https://www.epidemvac.ru/jour/article/view/394

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spelling	doaj-5782d9c4bfc84aad9c785ba3252a453b2021-07-28T13:31:49ZrusNumikom LLCЭпидемиология и вакцинопрофилактика2073-30462619-04942018-02-01171202410.31631/2073-3046-2018-17-1-20-24392Evaluation of the Reactogenicity, Safety and Immunogenicity of the Domestic Influenza Inactivated Split FLU-M Vaccine in Immunization Adults aged 18–60 YearsI. V. Fel'dblyum0S. D. Novgorodova1G. M. Ignat'ev2S. O. Golodnova3V. P. Trukhin4S. Ya Melnikov5Federal State Educational Institution of Higher Education «Perm State Medical University named after Academician E. A. Wagner» of the Ministry of Healthcare of the Russian FederationFederal State Educational Institution of Higher Education «Perm State Medical University named after Academician E. A. Wagner» of the Ministry of Healthcare of the Russian FederationThe Federal State Unitary Enterprise «St. Petersburg Research Institute of Vaccines and Serums and the Bacterial Preparation Factory» of the Russian Federal Biomedical Agency Federal Medical Biological AgencyFederal State Educational Institution of Higher Education «Perm State Medical University named after Academician E. A. Wagner» of the Ministry of Healthcare of the Russian FederationThe Federal State Unitary Enterprise «St. Petersburg Research Institute of Vaccines and Serums and the Bacterial Preparation Factory» of the Russian Federal Biomedical Agency Federal Medical Biological AgencyThe Federal State Unitary Enterprise «St. Petersburg Research Institute of Vaccines and Serums and the Bacterial Preparation Factory» of the Russian Federal Biomedical Agency Federal Medical Biological AgencyThis article presents the results of a simple, blind, randomized, placebo-controlled, single-center, prospective research of the reactogenicity, safety, and immunogenicity of the domestic influenza inactivated split vaccine «Flu-M» in immunization of the adult population of 18–60 years old. Low reactogenicity, high safety profile and immunogenicity of the Flu-M vaccine were determined.https://www.epidemvac.ru/jour/article/view/394vaccine against influenza flu-madult population of 18–60 years oldsafetyreactogenicityimmunogenicity
collection	DOAJ
language	Russian
format	Article
sources	DOAJ
author	I. V. Fel'dblyum S. D. Novgorodova G. M. Ignat'ev S. O. Golodnova V. P. Trukhin S. Ya Melnikov
spellingShingle	I. V. Fel'dblyum S. D. Novgorodova G. M. Ignat'ev S. O. Golodnova V. P. Trukhin S. Ya Melnikov Evaluation of the Reactogenicity, Safety and Immunogenicity of the Domestic Influenza Inactivated Split FLU-M Vaccine in Immunization Adults aged 18–60 Years Эпидемиология и вакцинопрофилактика vaccine against influenza flu-m adult population of 18–60 years old safety reactogenicity immunogenicity
author_facet	I. V. Fel'dblyum S. D. Novgorodova G. M. Ignat'ev S. O. Golodnova V. P. Trukhin S. Ya Melnikov
author_sort	I. V. Fel'dblyum
title	Evaluation of the Reactogenicity, Safety and Immunogenicity of the Domestic Influenza Inactivated Split FLU-M Vaccine in Immunization Adults aged 18–60 Years
title_short	Evaluation of the Reactogenicity, Safety and Immunogenicity of the Domestic Influenza Inactivated Split FLU-M Vaccine in Immunization Adults aged 18–60 Years
title_full	Evaluation of the Reactogenicity, Safety and Immunogenicity of the Domestic Influenza Inactivated Split FLU-M Vaccine in Immunization Adults aged 18–60 Years
title_fullStr	Evaluation of the Reactogenicity, Safety and Immunogenicity of the Domestic Influenza Inactivated Split FLU-M Vaccine in Immunization Adults aged 18–60 Years
title_full_unstemmed	Evaluation of the Reactogenicity, Safety and Immunogenicity of the Domestic Influenza Inactivated Split FLU-M Vaccine in Immunization Adults aged 18–60 Years
title_sort	evaluation of the reactogenicity, safety and immunogenicity of the domestic influenza inactivated split flu-m vaccine in immunization adults aged 18–60 years
publisher	Numikom LLC
series	Эпидемиология и вакцинопрофилактика
issn	2073-3046 2619-0494
publishDate	2018-02-01
description	This article presents the results of a simple, blind, randomized, placebo-controlled, single-center, prospective research of the reactogenicity, safety, and immunogenicity of the domestic influenza inactivated split vaccine «Flu-M» in immunization of the adult population of 18–60 years old. Low reactogenicity, high safety profile and immunogenicity of the Flu-M vaccine were determined.
topic	vaccine against influenza flu-m adult population of 18–60 years old safety reactogenicity immunogenicity
url	https://www.epidemvac.ru/jour/article/view/394
work_keys_str_mv	AT ivfeldblyum evaluationofthereactogenicitysafetyandimmunogenicityofthedomesticinfluenzainactivatedsplitflumvaccineinimmunizationadultsaged1860years AT sdnovgorodova evaluationofthereactogenicitysafetyandimmunogenicityofthedomesticinfluenzainactivatedsplitflumvaccineinimmunizationadultsaged1860years AT gmignatev evaluationofthereactogenicitysafetyandimmunogenicityofthedomesticinfluenzainactivatedsplitflumvaccineinimmunizationadultsaged1860years AT sogolodnova evaluationofthereactogenicitysafetyandimmunogenicityofthedomesticinfluenzainactivatedsplitflumvaccineinimmunizationadultsaged1860years AT vptrukhin evaluationofthereactogenicitysafetyandimmunogenicityofthedomesticinfluenzainactivatedsplitflumvaccineinimmunizationadultsaged1860years AT syamelnikov evaluationofthereactogenicitysafetyandimmunogenicityofthedomesticinfluenzainactivatedsplitflumvaccineinimmunizationadultsaged1860years
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Evaluation of the Reactogenicity, Safety and Immunogenicity of the Domestic Influenza Inactivated Split FLU-M Vaccine in Immunization Adults aged 18–60 Years

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