Circulating Exosomes Inhibit B Cell Proliferation and Activity

Circulating Exosomes Inhibit B Cell Proliferation and Activity

(1) Background: Head and neck squamous cell carcinoma (HNSCC) is characterized by a distinctive suppression of the anti-tumor immunity, both locally in the tumor microenvironment (TME) and the periphery. Tumor-derived exosomes mediate this immune suppression by directly suppressing T effector functi...

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Bibliographic Details
Main Authors: Jan C. Schroeder, Lisa Puntigam, Linda Hofmann, Sandra S. Jeske, Inga J. Beccard, Johannes Doescher, Simon Laban, Thomas K. Hoffmann, Cornelia Brunner, Marie-Nicole Theodoraki, Patrick J. Schuler
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Cancers
Subjects:
exosomes
B cells
Head and Neck Cancer
Bruton’s tyrosine kinase
Online Access:https://www.mdpi.com/2072-6694/12/8/2110

Internet

https://www.mdpi.com/2072-6694/12/8/2110

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