Bone Marrow-Derived Mononuclear Cell Therapy in Papain-Induced Experimental Pulmonary Emphysema

Bone Marrow-Derived Mononuclear Cell Therapy in Papain-Induced Experimental Pulmonary Emphysema

Murine papain-induced emphysema is a model that reproduces many of the features found in patients. Bone marrow-derived mononuclear cells (BMMC) have already been used to repair the alveolar epithelium in respiratory diseases, but not in the papain model. Thus, we hypothesized that BMMC could prevent...

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Bibliographic Details
Main Authors: Mariana N. Machado, Flavia Mazzoli-Rocha, Natália V. Casquilho, Tatiana Maron-Gutierrez, Victor H. Ortenzi, Marcelo M. Morales, Rodrigo S. Fortunato, Walter A. Zin
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Physiology
Subjects:
pulmonary emphysema
papain
bone marrow-derived mononuclear cells
lung mechanics
histology
apoptosis
Online Access:http://journal.frontiersin.org/article/10.3389/fphys.2018.00121/full

Internet

http://journal.frontiersin.org/article/10.3389/fphys.2018.00121/full

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