Radiation Esophagitis in a Patient with Oral Carcinoma and Bone Metastasis
Radiation esophagitis requiring endoscopic evaluation occurs quite rarely, affecting <1% of patients undergoing radiation treatment. Acute radiation esophagitis develops within 3 weeks of radiation therapy. We describe herein a case of radiation esophagitis in a patient with oral carcinoma...
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2020-09-01
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doaj-5893d70e5bd848bfaa2c64397825ab772020-11-25T03:56:15ZengKarger PublishersCase Reports in Gastroenterology1662-06312020-09-0114345345710.1159/000508930508930Radiation Esophagitis in a Patient with Oral Carcinoma and Bone MetastasisToshimi ChibaYu OhashiNaoko TsunodaKei OnoderaTadashi KawaiIkuya MiyamotoHiroyuki YamadaRadiation esophagitis requiring endoscopic evaluation occurs quite rarely, affecting <1% of patients undergoing radiation treatment. Acute radiation esophagitis develops within 3 weeks of radiation therapy. We describe herein a case of radiation esophagitis in a patient with oral carcinoma with multiple general bone metastases. Cisplatin, fluorouracil, and cetuximab were given for 3 cycles. Radiation therapy (30 Gy) to the thoracic vertebrae and lumbar vertebrae was prescribed to prevent worsening of bone metastases and relieve pain. Neutropenia was also observed due to chemotherapy. After the end of radiation therapy, the patient experienced chest pain, heartburn, and dysphagia. Upper gastrointestinal endoscopy revealed severe radiation esophagitis of endoscopic Fukui Acute Radiation Esophagitis grade 4. Oral food was discontinued and an intravenous proton-pump inhibitor was administered. After 3 weeks, upper gastrointestinal endoscopy showed improvement of radiation esophagitis, with scars. The symptoms of chest pain, heartburn, and dysphagia had also disappeared. This is the first case to be reported of acute radiation esophagitis in a patient with oral carcinoma with bone metastasis who experienced dramatic improvement of endoscopic findings. Neutropenia appears to be associated with more severe acute radiation esophagitis.https://www.karger.com/Article/FullText/508930radiation esophagitisoral carcinomabone metastasis |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Toshimi Chiba Yu Ohashi Naoko Tsunoda Kei Onodera Tadashi Kawai Ikuya Miyamoto Hiroyuki Yamada |
spellingShingle |
Toshimi Chiba Yu Ohashi Naoko Tsunoda Kei Onodera Tadashi Kawai Ikuya Miyamoto Hiroyuki Yamada Radiation Esophagitis in a Patient with Oral Carcinoma and Bone Metastasis Case Reports in Gastroenterology radiation esophagitis oral carcinoma bone metastasis |
author_facet |
Toshimi Chiba Yu Ohashi Naoko Tsunoda Kei Onodera Tadashi Kawai Ikuya Miyamoto Hiroyuki Yamada |
author_sort |
Toshimi Chiba |
title |
Radiation Esophagitis in a Patient with Oral Carcinoma and Bone Metastasis |
title_short |
Radiation Esophagitis in a Patient with Oral Carcinoma and Bone Metastasis |
title_full |
Radiation Esophagitis in a Patient with Oral Carcinoma and Bone Metastasis |
title_fullStr |
Radiation Esophagitis in a Patient with Oral Carcinoma and Bone Metastasis |
title_full_unstemmed |
Radiation Esophagitis in a Patient with Oral Carcinoma and Bone Metastasis |
title_sort |
radiation esophagitis in a patient with oral carcinoma and bone metastasis |
publisher |
Karger Publishers |
series |
Case Reports in Gastroenterology |
issn |
1662-0631 |
publishDate |
2020-09-01 |
description |
Radiation esophagitis requiring endoscopic evaluation occurs quite rarely, affecting <1% of patients undergoing radiation treatment. Acute radiation esophagitis develops within 3 weeks of radiation therapy. We describe herein a case of radiation esophagitis in a patient with oral carcinoma with multiple general bone metastases. Cisplatin, fluorouracil, and cetuximab were given for 3 cycles. Radiation therapy (30 Gy) to the thoracic vertebrae and lumbar vertebrae was prescribed to prevent worsening of bone metastases and relieve pain. Neutropenia was also observed due to chemotherapy. After the end of radiation therapy, the patient experienced chest pain, heartburn, and dysphagia. Upper gastrointestinal endoscopy revealed severe radiation esophagitis of endoscopic Fukui Acute Radiation Esophagitis grade 4. Oral food was discontinued and an intravenous proton-pump inhibitor was administered. After 3 weeks, upper gastrointestinal endoscopy showed improvement of radiation esophagitis, with scars. The symptoms of chest pain, heartburn, and dysphagia had also disappeared. This is the first case to be reported of acute radiation esophagitis in a patient with oral carcinoma with bone metastasis who experienced dramatic improvement of endoscopic findings. Neutropenia appears to be associated with more severe acute radiation esophagitis. |
topic |
radiation esophagitis oral carcinoma bone metastasis |
url |
https://www.karger.com/Article/FullText/508930 |
work_keys_str_mv |
AT toshimichiba radiationesophagitisinapatientwithoralcarcinomaandbonemetastasis AT yuohashi radiationesophagitisinapatientwithoralcarcinomaandbonemetastasis AT naokotsunoda radiationesophagitisinapatientwithoralcarcinomaandbonemetastasis AT keionodera radiationesophagitisinapatientwithoralcarcinomaandbonemetastasis AT tadashikawai radiationesophagitisinapatientwithoralcarcinomaandbonemetastasis AT ikuyamiyamoto radiationesophagitisinapatientwithoralcarcinomaandbonemetastasis AT hiroyukiyamada radiationesophagitisinapatientwithoralcarcinomaandbonemetastasis |
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