Impact of Influenza on Pneumococcal Vaccine Effectiveness during <i>Streptococcus pneumoniae</i> Infection in Aged Murine Lung

Changes in innate and adaptive immune responses caused by viral imprinting can have a significant direct or indirect influence on secondary infections and vaccine responses. The purpose of our current study was to investigate the role of immune imprinting by influenza on pneumococcal vaccine effecti...

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Bibliographic Details
Main Authors: Ermias Jirru, Stefi Lee, Rebecca Harris, Jianjun Yang, Soo Jung Cho, Heather Stout-Delgado
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/8/2/298