Aging-related motor function and dopaminergic neuronal loss in C57BL/6 mice

Aging-related motor function and dopaminergic neuronal loss in C57BL/6 mice

Abstract Aging-related dopaminergic neuronal loss and its motor phenotypes are well known. Excessive loss of dopaminergic neurons leads to Parkinson’s disease (PD), the most common neurodegenerative disorder characterized by the loss of nigrostriatal dopamine–producing neurons. In mice, however, agi...

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Bibliographic Details
Main Authors: Sachiko Noda, Shigeto Sato, Takahiro Fukuda, Norihiro Tada, Nobutaka Hattori
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Molecular Brain
Subjects:
Dopaminergic neuron
C57BL/6 mouse
Aging
Mitochondria
Online Access:http://link.springer.com/article/10.1186/s13041-020-00585-6

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