GATA2 mutation in long stand Mycobacterium kansasii infection, myelodysplasia and MonoMAC syndrome: a case-report

GATA2 mutation in long stand Mycobacterium kansasii infection, myelodysplasia and MonoMAC syndrome: a case-report

Abstract Background GATA2 is a transcription factor that is a critical regulator of gene expression in hematopoietic cells. GATA2 deficiency presents with multi-lineage cytopenia, mycobacterial, fungal and viral infections. Patients with GATA2 mutation have a high risk of developing myelodysplastic...

Full description

Bibliographic Details
Main Authors: Daniela Palheiro Mendes-de-Almeida, Francianne Gomes Andrade, Gustavo Borges, Filipe V. dos Santos-Bueno, Iracema F. Vieira, Luana Kelly M. da S. da Rocha, Daniella A. Mendes-da-Cruz, Rosely M. Zancopé-Oliveira, Rodrigo T. Calado, Maria S. Pombo-de-Oliveira
Format: Article
Language:English
Published: BMC 2019-04-01
Series:BMC Medical Genetics
Subjects:
GATA-2 mutation
MonoMAC syndrome
Myelodysplastic syndrome
Myelodysplasia
Mycobacterium kansasii
Online Access:http://link.springer.com/article/10.1186/s12881-019-0799-6

Internet

http://link.springer.com/article/10.1186/s12881-019-0799-6

Similar Items