Nivolumab‐induced celiac‐like enteropathy in patient with metastatic renal cell carcinoma: Case report and review of the literature
Abstract Nivolumab may induce severe celiac‐like enteropathy, that may appear very rapidly, after only two injections of nivolumab, and may be successfully treated with corticosteroids. This observation underlines the importance of histological analysis of duodenal biopsies and the necessity to rule...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2019-09-01
|
| Series: | Clinical Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/ccr3.2342 |
| id |
doaj-58e2536996b5436781aa9b2f5d0bafee |
|---|---|
| record_format |
Article |
| spelling |
doaj-58e2536996b5436781aa9b2f5d0bafee2020-11-24T21:11:28ZengWileyClinical Case Reports2050-09042019-09-01791689169310.1002/ccr3.2342Nivolumab‐induced celiac‐like enteropathy in patient with metastatic renal cell carcinoma: Case report and review of the literatureLucie Duval0Sarah Habes1Thierry Chatellier2Pascale Guerzider3Céline Bossard4Claude Masliah5Isabelle Archambeaud6Yann Touchefeu7Tamara Matysiak‐Budnik8IMAD, Hepato‐Gastroenterology & Digestive Oncology Hôtel Dieu, CHU de Nantes Nantes FranceIMAD, Hepato‐Gastroenterology & Digestive Oncology Hôtel Dieu, CHU de Nantes Nantes FranceClinic of Estuaire Saint Nazaire FranceDepartment of Pathology Hospital of Saint Nazaire Saint Nazaire FranceDepartment of Pathology University Hospital of Nantes Nantes FranceClinic of Estuaire Saint Nazaire FranceIMAD, Hepato‐Gastroenterology & Digestive Oncology Hôtel Dieu, CHU de Nantes Nantes FranceIMAD, Hepato‐Gastroenterology & Digestive Oncology Hôtel Dieu, CHU de Nantes Nantes FranceIMAD, Hepato‐Gastroenterology & Digestive Oncology Hôtel Dieu, CHU de Nantes Nantes FranceAbstract Nivolumab may induce severe celiac‐like enteropathy, that may appear very rapidly, after only two injections of nivolumab, and may be successfully treated with corticosteroids. This observation underlines the importance of histological analysis of duodenal biopsies and the necessity to rule out a real celiac disease in patients with nivolumab‐induced diarrhea.https://doi.org/10.1002/ccr3.2342celiac‐like enteropathyimmune‐related adverse effectsimmunotherapynivolumabPD‐1 inhibitors |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Lucie Duval Sarah Habes Thierry Chatellier Pascale Guerzider Céline Bossard Claude Masliah Isabelle Archambeaud Yann Touchefeu Tamara Matysiak‐Budnik |
| spellingShingle |
Lucie Duval Sarah Habes Thierry Chatellier Pascale Guerzider Céline Bossard Claude Masliah Isabelle Archambeaud Yann Touchefeu Tamara Matysiak‐Budnik Nivolumab‐induced celiac‐like enteropathy in patient with metastatic renal cell carcinoma: Case report and review of the literature Clinical Case Reports celiac‐like enteropathy immune‐related adverse effects immunotherapy nivolumab PD‐1 inhibitors |
| author_facet |
Lucie Duval Sarah Habes Thierry Chatellier Pascale Guerzider Céline Bossard Claude Masliah Isabelle Archambeaud Yann Touchefeu Tamara Matysiak‐Budnik |
| author_sort |
Lucie Duval |
| title |
Nivolumab‐induced celiac‐like enteropathy in patient with metastatic renal cell carcinoma: Case report and review of the literature |
| title_short |
Nivolumab‐induced celiac‐like enteropathy in patient with metastatic renal cell carcinoma: Case report and review of the literature |
| title_full |
Nivolumab‐induced celiac‐like enteropathy in patient with metastatic renal cell carcinoma: Case report and review of the literature |
| title_fullStr |
Nivolumab‐induced celiac‐like enteropathy in patient with metastatic renal cell carcinoma: Case report and review of the literature |
| title_full_unstemmed |
Nivolumab‐induced celiac‐like enteropathy in patient with metastatic renal cell carcinoma: Case report and review of the literature |
| title_sort |
nivolumab‐induced celiac‐like enteropathy in patient with metastatic renal cell carcinoma: case report and review of the literature |
| publisher |
Wiley |
| series |
Clinical Case Reports |
| issn |
2050-0904 |
| publishDate |
2019-09-01 |
| description |
Abstract Nivolumab may induce severe celiac‐like enteropathy, that may appear very rapidly, after only two injections of nivolumab, and may be successfully treated with corticosteroids. This observation underlines the importance of histological analysis of duodenal biopsies and the necessity to rule out a real celiac disease in patients with nivolumab‐induced diarrhea. |
| topic |
celiac‐like enteropathy immune‐related adverse effects immunotherapy nivolumab PD‐1 inhibitors |
| url |
https://doi.org/10.1002/ccr3.2342 |
| work_keys_str_mv |
AT lucieduval nivolumabinducedceliaclikeenteropathyinpatientwithmetastaticrenalcellcarcinomacasereportandreviewoftheliterature AT sarahhabes nivolumabinducedceliaclikeenteropathyinpatientwithmetastaticrenalcellcarcinomacasereportandreviewoftheliterature AT thierrychatellier nivolumabinducedceliaclikeenteropathyinpatientwithmetastaticrenalcellcarcinomacasereportandreviewoftheliterature AT pascaleguerzider nivolumabinducedceliaclikeenteropathyinpatientwithmetastaticrenalcellcarcinomacasereportandreviewoftheliterature AT celinebossard nivolumabinducedceliaclikeenteropathyinpatientwithmetastaticrenalcellcarcinomacasereportandreviewoftheliterature AT claudemasliah nivolumabinducedceliaclikeenteropathyinpatientwithmetastaticrenalcellcarcinomacasereportandreviewoftheliterature AT isabellearchambeaud nivolumabinducedceliaclikeenteropathyinpatientwithmetastaticrenalcellcarcinomacasereportandreviewoftheliterature AT yanntouchefeu nivolumabinducedceliaclikeenteropathyinpatientwithmetastaticrenalcellcarcinomacasereportandreviewoftheliterature AT tamaramatysiakbudnik nivolumabinducedceliaclikeenteropathyinpatientwithmetastaticrenalcellcarcinomacasereportandreviewoftheliterature |
| _version_ |
1716753244048326656 |