Primary Signet-Ring Cell Adenocarcinoma of the Urinary Bladder Treated with Partial Cystectomy: A Case Report and Review of the Literature
Primary signet-ring cell carcinoma is a variant of adenocarcinoma which is extremely rare, associated with poor prognosis and generally found to be resistant to chemotherapy and radiotherapy. We report a case of primary signet-ring cell carcinoma of the bladder which was successfully treated with pa...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2017-01-01
|
Series: | Case Reports in Urology |
Online Access: | http://dx.doi.org/10.1155/2017/6829692 |
id |
doaj-5908727bd2a749c497b68f3dadb66423 |
---|---|
record_format |
Article |
spelling |
doaj-5908727bd2a749c497b68f3dadb664232020-11-24T23:06:03ZengHindawi LimitedCase Reports in Urology2090-696X2090-69782017-01-01201710.1155/2017/68296926829692Primary Signet-Ring Cell Adenocarcinoma of the Urinary Bladder Treated with Partial Cystectomy: A Case Report and Review of the LiteratureUmesh Jayarajah0D. M. Hilary Fernando1Kasun Bandara Herath2M. V. Chandu de Silva3S. A. S. Goonewardena4Department of Urology, National Hospital of Sri Lanka, Colombo, Sri LankaDepartment of Urology, National Hospital of Sri Lanka, Colombo, Sri LankaDepartment of Urology, National Hospital of Sri Lanka, Colombo, Sri LankaDepartment of Pathology, Faculty of Medicine, University of Colombo, Colombo, Sri LankaDepartment of Urology, National Hospital of Sri Lanka, Colombo, Sri LankaPrimary signet-ring cell carcinoma is a variant of adenocarcinoma which is extremely rare, associated with poor prognosis and generally found to be resistant to chemotherapy and radiotherapy. We report a case of primary signet-ring cell carcinoma of the bladder which was successfully treated with partial cystectomy. A 71-year-old female with a history of type 2 diabetes, hypertension, and ischaemic heart disease presented with painless haematuria for 2 months’ duration. The abdominal ultrasonography showed a localised polypoidal vesical growth arising from the bladder dome. Cystoscopy revealed an exophytic solid tumour in the anterior fundal wall. A deep transurethral resection of bladder tumour was done and histology revealed an adenocarcinoma composed of mucinous and signet-ring cell components. Later, considering the patient’s age and the poor general condition, a partial cystectomy was done. Follow-up cystoscopy and ultrasonography were done at 12 months and there was no evidence of tumour recurrence and the patient is currently symptom-free. Partial cystectomy may be considered in patients with localised tumour without evidence of metastasis and poor general condition. Regular cystoscopies and ultrasound imaging are necessary for follow-up and early identification of recurrences.http://dx.doi.org/10.1155/2017/6829692 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Umesh Jayarajah D. M. Hilary Fernando Kasun Bandara Herath M. V. Chandu de Silva S. A. S. Goonewardena |
spellingShingle |
Umesh Jayarajah D. M. Hilary Fernando Kasun Bandara Herath M. V. Chandu de Silva S. A. S. Goonewardena Primary Signet-Ring Cell Adenocarcinoma of the Urinary Bladder Treated with Partial Cystectomy: A Case Report and Review of the Literature Case Reports in Urology |
author_facet |
Umesh Jayarajah D. M. Hilary Fernando Kasun Bandara Herath M. V. Chandu de Silva S. A. S. Goonewardena |
author_sort |
Umesh Jayarajah |
title |
Primary Signet-Ring Cell Adenocarcinoma of the Urinary Bladder Treated with Partial Cystectomy: A Case Report and Review of the Literature |
title_short |
Primary Signet-Ring Cell Adenocarcinoma of the Urinary Bladder Treated with Partial Cystectomy: A Case Report and Review of the Literature |
title_full |
Primary Signet-Ring Cell Adenocarcinoma of the Urinary Bladder Treated with Partial Cystectomy: A Case Report and Review of the Literature |
title_fullStr |
Primary Signet-Ring Cell Adenocarcinoma of the Urinary Bladder Treated with Partial Cystectomy: A Case Report and Review of the Literature |
title_full_unstemmed |
Primary Signet-Ring Cell Adenocarcinoma of the Urinary Bladder Treated with Partial Cystectomy: A Case Report and Review of the Literature |
title_sort |
primary signet-ring cell adenocarcinoma of the urinary bladder treated with partial cystectomy: a case report and review of the literature |
publisher |
Hindawi Limited |
series |
Case Reports in Urology |
issn |
2090-696X 2090-6978 |
publishDate |
2017-01-01 |
description |
Primary signet-ring cell carcinoma is a variant of adenocarcinoma which is extremely rare, associated with poor prognosis and generally found to be resistant to chemotherapy and radiotherapy. We report a case of primary signet-ring cell carcinoma of the bladder which was successfully treated with partial cystectomy. A 71-year-old female with a history of type 2 diabetes, hypertension, and ischaemic heart disease presented with painless haematuria for 2 months’ duration. The abdominal ultrasonography showed a localised polypoidal vesical growth arising from the bladder dome. Cystoscopy revealed an exophytic solid tumour in the anterior fundal wall. A deep transurethral resection of bladder tumour was done and histology revealed an adenocarcinoma composed of mucinous and signet-ring cell components. Later, considering the patient’s age and the poor general condition, a partial cystectomy was done. Follow-up cystoscopy and ultrasonography were done at 12 months and there was no evidence of tumour recurrence and the patient is currently symptom-free. Partial cystectomy may be considered in patients with localised tumour without evidence of metastasis and poor general condition. Regular cystoscopies and ultrasound imaging are necessary for follow-up and early identification of recurrences. |
url |
http://dx.doi.org/10.1155/2017/6829692 |
work_keys_str_mv |
AT umeshjayarajah primarysignetringcelladenocarcinomaoftheurinarybladdertreatedwithpartialcystectomyacasereportandreviewoftheliterature AT dmhilaryfernando primarysignetringcelladenocarcinomaoftheurinarybladdertreatedwithpartialcystectomyacasereportandreviewoftheliterature AT kasunbandaraherath primarysignetringcelladenocarcinomaoftheurinarybladdertreatedwithpartialcystectomyacasereportandreviewoftheliterature AT mvchandudesilva primarysignetringcelladenocarcinomaoftheurinarybladdertreatedwithpartialcystectomyacasereportandreviewoftheliterature AT sasgoonewardena primarysignetringcelladenocarcinomaoftheurinarybladdertreatedwithpartialcystectomyacasereportandreviewoftheliterature |
_version_ |
1725624095902531584 |