Efficient conversion of chemical energy into mechanical work by Hsp70 chaperones

Efficient conversion of chemical energy into mechanical work by Hsp70 chaperones

Hsp70 molecular chaperones are abundant ATP-dependent nanomachines that actively reshape non-native, misfolded proteins and assist a wide variety of essential cellular processes. Here, we combine complementary theoretical approaches to elucidate the structural and thermodynamic details of the chaper...

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Bibliographic Details
Main Authors: Salvatore Assenza, Alberto Stefano Sassi, Ruth Kellner, Benjamin Schuler, Paolo De Los Rios, Alessandro Barducci
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-12-01
Series:eLife
Subjects:
non-equilibrium thermodynamics
molecular chaperones
molecular simulations
Online Access:https://elifesciences.org/articles/48491

Internet

https://elifesciences.org/articles/48491

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