Cell-Specific PEAR1 Methylation Studies Reveal a Locus that Coordinates Expression of Multiple Genes

Cell-Specific PEAR1 Methylation Studies Reveal a Locus that Coordinates Expression of Multiple Genes

Chromosomal interactions connect distant enhancers and promoters on the same chromosome, activating or repressing gene expression. PEAR1 encodes the Platelet-Endothelial Aggregation Receptor 1, a contact receptor involved in platelet function and megakaryocyte and endothelial cell proliferation. PEA...

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Bibliographic Details
Main Authors: Benedetta Izzi, Fabrizia Noro, Katrien Cludts, Kathleen Freson, Marc F. Hoylaerts
Format: Article
Language:English
Published: MDPI AG 2018-04-01
Series:International Journal of Molecular Sciences
Subjects:
PEAR1
DNA methylation
chromosome interactions
Online Access:http://www.mdpi.com/1422-0067/19/4/1069

Internet

http://www.mdpi.com/1422-0067/19/4/1069

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