Diacylglycerol acyltransferase-1 inhibition enhances intestinal fatty acid oxidation and reduces energy intake in rats[S]

Diacylglycerol acyltransferase-1 inhibition enhances intestinal fatty acid oxidation and reduces energy intake in rats[S]

Acyl CoA:diacylglycerol acyltransferase-1 (DGAT-1) catalyzes the final step in triacylglycerol (TAG) synthesis and is highly expressed in the small intestine. Because DGAT-1 knockout mice are resistant to diet-induced obesity, we investigated the acute effects of intragastric (IG) infusion of a smal...

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Bibliographic Details
Main Authors: Gudrun Schober, Myrtha Arnold, Susan Birtles, Linda K. Buckett, Gustavo Pacheco-López, Andrew V. Turnbull, Wolfgang Langhans, Abdelhak Mansouri
Format: Article
Language:English
Published: Elsevier 2013-05-01
Series:Journal of Lipid Research
Subjects:
triacylglycerol
ketogenesis
small intestine
enterocytes
high fat diet
eating
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520421741

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520421741

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