Skeletal Muscle Loss during Multikinase Inhibitors Therapy: Molecular Pathways, Clinical Implications, and Nutritional Challenges

In cancer patients, loss of muscle mass is significantly associated with low tolerability of chemotherapy and poor survival. Despite the great strides in the treatment of cancer, targeted therapies such as tyrosine kinase inhibitors (TKIs) could exacerbate muscle wasting. Over recent years, the impa...

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Bibliographic Details
Main Authors: Emanuele Rinninella, Marco Cintoni, Pauline Raoul, Carmelo Pozzo, Antonia Strippoli, Francesca Romana Ponziani, Maurizio Pompili, Emilio Bria, Giampaolo Tortora, Antonio Gasbarrini, Maria Cristina Mele
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Nutrients
Subjects:
Online Access:https://www.mdpi.com/2072-6643/12/10/3101