Ulinastatin May Significantly Improve Postoperative Cognitive Function of Elderly Patients Undergoing Spinal Surgery by Reducing the Translocation of Lipopolysaccharide and Systemic Inflammation

Ulinastatin May Significantly Improve Postoperative Cognitive Function of Elderly Patients Undergoing Spinal Surgery by Reducing the Translocation of Lipopolysaccharide and Systemic Inflammation

Background: Studies have shown that perioperative inflammatory response is one of the important factors that caused postoperative cognitive dysfunction (POCD). Ulinastatin is a broad-spectrum protease inhibitor that inhibits inflammatory. We investigated the effects of ulinastatin on inflammatory re...

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Bibliographic Details
Main Authors: Min Zhang, Yan-Hua Zhang, Hui-Qun Fu, Qing-Ming Zhang, Tian-Long Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Pharmacology
Subjects:
ulinastatin
elderly patients
spine surgery
lipopolysaccharide
systemic inflammation
POCD
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01007/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.01007/full

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