Recent progress in research of hepatitis B viruses with precore and basic core promoter mutations
Mutations in the precore and basic core promoter of hepatitis B virus (HBV) can reduce synthesis and secretion of the HBV e antigen (HBeAg), increase viral replication, and cause HBeAg-negative chronic hepatitis B (CHB). Therefore, these mutations are likely to have important impacts on the clinical...
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| Format: | Article |
| Language: | zho |
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Editorial Department of Journal of Clinical Hepatology
2013-02-01
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| Series: | Linchuang Gandanbing Zazhi |
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| Online Access: | http://www.lcgdbzz.org/qk_content.asp?id=5239&ClassID=115155828 |