Automated Quantification of Extranuclear ERα Using Phosphor-Integrated Dots for Predicting Endocrine Therapy Resistance in HR<sup>+</sup>/HER2<sup>−</sup> Breast Cancer

Automated Quantification of Extranuclear ERα Using Phosphor-Integrated Dots for Predicting Endocrine Therapy Resistance in HR<sup>+</sup>/HER2<sup>−</sup> Breast Cancer

In addition to genomic signaling, Estrogen receptor alpha (ER&#945;) is associated with cell proliferation and survival through extranuclear signaling contributing to endocrine therapy (ET) resistance. However, the relationship between extranuclear ER&#945; and ET resistance has not been ext...

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Bibliographic Details
Main Authors: Zhaorong Guo, Hiroshi Tada, Narufumi Kitamura, Yoh Hamada, Minoru Miyashita, Narumi Harada-Shoji, Akiko Sato, Yohei Hamanaka, Kouki Tsuboi, Nobuhisa Harada, Mayumi Takano-Kasuya, Hisatake Okada, Yasushi Nakano, Noriaki Ohuchi, Shin-ichi Hayashi, Takanori Ishida, Kohsuke Gonda
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Cancers
Subjects:
breast cancer
estrogen receptor α
IHC-PIDs
prognostic
endocrine therapy resistance
Online Access:https://www.mdpi.com/2072-6694/11/4/526

Internet

https://www.mdpi.com/2072-6694/11/4/526

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