Characterization of Critical Determinants of ACE2–SARS CoV-2 RBD Interaction

Characterization of Critical Determinants of ACE2–SARS CoV-2 RBD Interaction

Despite sequence similarity to SARS-CoV-1, SARS-CoV-2 has demonstrated greater widespread virulence and unique challenges to researchers aiming to study its pathogenicity in humans. The interaction of the viral receptor binding domain (RBD) with its main host cell receptor, angiotensin-converting en...

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Bibliographic Details
Main Authors: Emily E. F. Brown, Reza Rezaei, Taylor R. Jamieson, Jaahnavi Dave, Nikolas T. Martin, Ragunath Singaravelu, Mathieu J. F. Crupi, Stephen Boulton, Sarah Tucker, Jessie Duong, Joanna Poutou, Adrian Pelin, Hamed Yasavoli-Sharahi, Zaid Taha, Rozanne Arulanandam, Abera Surendran, Mina Ghahremani, Bradley Austin, Chantal Matar, Jean-Simon Diallo, John C. Bell, Carolina S. Ilkow, Taha Azad
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
SARS-CoV-2
angiotensin-converting enzyme 2
receptor binding domain
NanoLuc Binary Technology
spike protein
vaccine development
Online Access:https://www.mdpi.com/1422-0067/22/5/2268

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