Novel Insights in Anti-CD38 Therapy Based on CD38-Receptor Expression and Function: The Multiple Myeloma Model

Novel Insights in Anti-CD38 Therapy Based on CD38-Receptor Expression and Function: The Multiple Myeloma Model

Multiple myeloma (MM) is a hematological disease characterized by the proliferation and accumulation of malignant plasmacells (PCs) in the bone marrow (BM). Despite widespread use of high-dose chemotherapy in combination with autologous stem cell transplantation (ASCT) and the introduction of novel...

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Bibliographic Details
Main Authors: Beatrice Anna Zannetti, Angelo Corso Faini, Evita Massari, Massimo Geuna, Enrico Maffini, Giovanni Poletti, Claudio Cerchione, Giovanni Martinelli, Fabio Malavasi, Francesco Lanza
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cells
Subjects:
CD38
plasmacells
multiple myeloma
CD38 antigen expression in various tissues
bone marrow microenvironment
anti-CD38 monoclonal antibodies
Online Access:https://www.mdpi.com/2073-4409/9/12/2666

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https://www.mdpi.com/2073-4409/9/12/2666

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