Intestinal α1-2-Fucosylation Contributes to Obesity and Steatohepatitis in MiceSummary

Intestinal α1-2-Fucosylation Contributes to Obesity and Steatohepatitis in MiceSummary

Background & Aims: Fucosyltransferase 2 (Fut2)-mediated intestinal α1- 2-fucosylation is important for host–microbe interactions and has been associated with several diseases, but its role in obesity and hepatic steatohepatitis is not known. The aim of this study was to investigate the role...

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Bibliographic Details
Main Authors: Rongrong Zhou, Cristina Llorente, Jinling Cao, Livia S. Zaramela, Suling Zeng, Bei Gao, Shang-Zhen Li, Ryan D. Welch, Feng-Qing Huang, Lian-Wen Qi, Chuyue Pan, Yan Huang, Pengchen Zhou, Iris Beussen, Ying Zhang, Gregory Bryam, Oliver Fiehn, Lirui Wang, E-Hu Liu, Ruth T. Yu, Michael Downes, Ronald M. Evans, Karrie Goglin, Derrick E. Fouts, David A. Brenner, Lars Bode, Xuegong Fan, Karsten Zengler, Bernd Schnabl
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
Metabolic Syndrome
Nonalcoholic Steatohepatitis
Microbiota
Metabolome
Bile Acids
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X21000424

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http://www.sciencedirect.com/science/article/pii/S2352345X21000424

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