Registration and Analysis of Bioelectric Activity of Sensory-Motor Cortex During the Electrical Stimulation of Nucleus Caudate in Rats
Background and purposeThe caudate circuit takes part in cognitive control of motor activity The purpose of the present work was registration and analysis of basic bioelectrical activity of ventral and dorsal sensory-motor cortex and nucleus caudate, study of the changes in EEG after nucleus caudate...
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doaj-5b2d5b991ee145e9ad89017f7ed0cd222020-11-24T21:16:08ZengAssociation of Basic Medical Sciences of Federation of Bosnia and HerzegovinaBosnian Journal of Basic Medical Sciences1512-86011840-48122007-05-017210.17305/bjbms.2007.3073645Registration and Analysis of Bioelectric Activity of Sensory-Motor Cortex During the Electrical Stimulation of Nucleus Caudate in RatsSnežana Medenica-Milanović0Siniša Ristić1Vladimir Turuntaš2Mirjana Mirić3Milan Kulić4Medical faculty Foća, University East SarajevoMedical faculty Foća, University East SarajevoMedical faculty Foća, University East SarajevoMedical faculty Foća, University East SarajevoMedical faculty Foća, University East SarajevoBackground and purposeThe caudate circuit takes part in cognitive control of motor activity The purpose of the present work was registration and analysis of basic bioelectrical activity of ventral and dorsal sensory-motor cortex and nucleus caudate, study of the changes in EEG after nucleus caudate electrical stimulation and to identify of threshold level of electrical stimuli responsible for changes of electrical activity in registered brain area. Materials and methodsWe used 28 albino Wistar rat of both genders. After the animal fixation on stereotaxic apparatus to dry bone, the places for electrode fixation were marked. Two days after the electrodes had been implanted an EEG was registered so that the animals would adjust to the conditions and so they would repair the tissue reactions. EEG was registered with bipolar electrodes with ten-channeled apparatus. For first half an hour spontaneous activity of the brain was registered, and after that the head of nucleus caudate was stimulated with altered impulses of various voltages, frequency and duration. Results and conclusionsThreshold values of electric stimulus intensity from 3 to 5 V, frequency from 3 to 5 Hz, duration from 3 to 5 ms, by stimulation the head of nucleus caudate of rat, lead to the change of basal bioelectric activity of cerebrum. The change of bioelectric activity is firstly recorded in equilateral cortex, and with the higher intensity of the stimulus the changes overtake the contra lateral cortex. http://www.bjbms.org/ojs/index.php/bjbms/article/view/3073nucleusc caudatebasal bioelectric activitysensory-motor cortex |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Snežana Medenica-Milanović Siniša Ristić Vladimir Turuntaš Mirjana Mirić Milan Kulić |
spellingShingle |
Snežana Medenica-Milanović Siniša Ristić Vladimir Turuntaš Mirjana Mirić Milan Kulić Registration and Analysis of Bioelectric Activity of Sensory-Motor Cortex During the Electrical Stimulation of Nucleus Caudate in Rats Bosnian Journal of Basic Medical Sciences nucleusc caudate basal bioelectric activity sensory-motor cortex |
author_facet |
Snežana Medenica-Milanović Siniša Ristić Vladimir Turuntaš Mirjana Mirić Milan Kulić |
author_sort |
Snežana Medenica-Milanović |
title |
Registration and Analysis of Bioelectric Activity of Sensory-Motor Cortex During the Electrical Stimulation of Nucleus Caudate in Rats |
title_short |
Registration and Analysis of Bioelectric Activity of Sensory-Motor Cortex During the Electrical Stimulation of Nucleus Caudate in Rats |
title_full |
Registration and Analysis of Bioelectric Activity of Sensory-Motor Cortex During the Electrical Stimulation of Nucleus Caudate in Rats |
title_fullStr |
Registration and Analysis of Bioelectric Activity of Sensory-Motor Cortex During the Electrical Stimulation of Nucleus Caudate in Rats |
title_full_unstemmed |
Registration and Analysis of Bioelectric Activity of Sensory-Motor Cortex During the Electrical Stimulation of Nucleus Caudate in Rats |
title_sort |
registration and analysis of bioelectric activity of sensory-motor cortex during the electrical stimulation of nucleus caudate in rats |
publisher |
Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina |
series |
Bosnian Journal of Basic Medical Sciences |
issn |
1512-8601 1840-4812 |
publishDate |
2007-05-01 |
description |
Background and purposeThe caudate circuit takes part in cognitive control of motor activity The purpose of the present work was registration and analysis of basic bioelectrical activity of ventral and dorsal sensory-motor cortex and nucleus caudate, study of the changes in EEG after nucleus caudate electrical stimulation and to identify of threshold level of electrical stimuli responsible for changes of electrical activity in registered brain area.
Materials and methodsWe used 28 albino Wistar rat of both genders. After the animal fixation on stereotaxic apparatus to dry bone, the places for electrode fixation were marked. Two days after the electrodes had been implanted an EEG was registered so that the animals would adjust to the conditions and so they would repair the tissue reactions. EEG was registered with bipolar electrodes with ten-channeled apparatus. For first half an hour spontaneous activity of the brain was registered, and after that the head of nucleus caudate was stimulated with altered impulses of various voltages, frequency and duration.
Results and conclusionsThreshold values of electric stimulus intensity from 3 to 5 V, frequency from 3 to 5 Hz, duration from 3 to 5 ms, by stimulation the head of nucleus caudate of rat, lead to the change of basal bioelectric activity of cerebrum. The change of bioelectric activity is firstly recorded in equilateral cortex, and with the higher intensity of the stimulus the changes overtake the contra lateral cortex.
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topic |
nucleusc caudate basal bioelectric activity sensory-motor cortex |
url |
http://www.bjbms.org/ojs/index.php/bjbms/article/view/3073 |
work_keys_str_mv |
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