Toosendanin Exerts an Anti-Cancer Effect in Glioblastoma by Inducing Estrogen Receptor β- and p53-Mediated Apoptosis

Toosendanin Exerts an Anti-Cancer Effect in Glioblastoma by Inducing Estrogen Receptor β- and p53-Mediated Apoptosis

Glioblastoma (GBM) is the most common primary brain tumor with median survival of approximately one year. This dismal poor prognosis is due to resistance to currently available chemotherapeutics; therefore, new cytotoxic agents are urgently needed. In the present study, we reported the cytotoxicity...

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Bibliographic Details
Main Authors: Liang Cao, Dingding Qu, Huan Wang, Sha Zhang, Chenming Jia, Zixuan Shi, Zongren Wang, Jian Zhang, Jing Ma
Format: Article
Language:English
Published: MDPI AG 2016-11-01
Series:International Journal of Molecular Sciences
Subjects:
glioblastoma
toosendanin
apoptosis
estrogen receptor β
p53
Online Access:http://www.mdpi.com/1422-0067/17/11/1928

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http://www.mdpi.com/1422-0067/17/11/1928

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