Regulation of CFTR Expression and Arginine Vasopressin Activity Are Dependent on Polycystin-1 in Kidney-Derived Cells

Regulation of CFTR Expression and Arginine Vasopressin Activity Are Dependent on Polycystin-1 in Kidney-Derived Cells

Background: Autosomal dominant polycystic kidney disease (ADPKD) is characterized by the development of multiple, progressive, fluid-filled renal cysts that distort the renal parenchyma, leading to end-stage renal failure, mainly after the fifth decade of life. ADPKD is caused by a mutation in the P...

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Bibliographic Details
Main Authors: Carolina Monteiro de Lemos Barbosa, Jackson Souza-Menezes, Andressa Godoy Amaral, Luiz Fernando Onuchic, Liudmila Cebotaru, William B. Guggino, Marcelo M. Morales
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-01-01
Series:Cellular Physiology and Biochemistry
Subjects:
CFTR
Kidney
Arginine vasopressin hormone
Polycystin
Autosomal dominant polycystic kidney disease
Online Access:http://www.karger.com/Article/FullText/438606

Internet

http://www.karger.com/Article/FullText/438606

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