Acute Tumor Response to ZD6126 Assessed by Intrinsic Susceptibility Magnetic Resonance Imaging

The effective magnetic resonance imaging (MRI) transverse relaxation rate R2* was investigated as an early acute marker of the response of rat GH3 prolactinomas to the vascular-targeting agent, ZD6126. Multigradient echo (MGRE) MRI was used to quantify R2*, which is sensitive to tissue deoxyhemoglo...

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Bibliographic Details
Main Authors: Simon P. Robinson, Tammy L. Kalber, Franklyn A. Howe, Dominick J.O. McIntyre, John R. Griffiths, David C. Blakey, Lynsey Whittaker, Anderson J. Ryan, John C. Waterton
Format: Article
Language:English
Published: Elsevier 2005-05-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
MRI
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558605800533