Protection of radiation-induced damage to the hematopoietic system, small intestine and salivary glands in rats by JNJ7777120 compound, a histamine H4 ligand.

Protection of radiation-induced damage to the hematopoietic system, small intestine and salivary glands in rats by JNJ7777120 compound, a histamine H4 ligand.

Based on previous data on the histamine radioprotective effect on highly radiosensitive tissues, in the present work we aimed at investigating the radioprotective potential of the H4R ligand, JNJ7777120, on ionizing radiation-induced injury and genotoxic damage in small intestine, salivary glands an...

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Bibliographic Details
Main Authors: Diego J Martinel Lamas, Eliana Carabajal, Juan P Prestifilippo, Luis Rossi, Juan C Elverdin, Susana Merani, Rosa M Bergoc, Elena S Rivera, Vanina A Medina
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3724844?pdf=render

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http://europepmc.org/articles/PMC3724844?pdf=render

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