Focus-ING on DNA Integrity: Implication of ING Proteins in Cell Cycle Regulation and DNA Repair Modulation

The ING family of tumor suppressor genes is composed of five members (ING1-5) involved in cell cycle regulation, DNA damage response, apoptosis and senescence. All ING proteins belong to various HAT or HDAC complexes and participate in chromatin remodeling that is essential for genomic stability and...

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Bibliographic Details
Main Authors: Jérôme Archambeau, Alice Blondel, Rémy Pedeux
Format: Article
Language:English
Published: MDPI AG 2019-12-01
Series:Cancers
Subjects:
p21
hr
Online Access:https://www.mdpi.com/2072-6694/12/1/58