The management of orthostatic hypotension in Parkinson's disease

Orthostatic hypotension is a common and disabling symptom affecting Parkinson’s disease (PD) patients. We present the effect of the different therapies commonly used to manage Parkinson’s disease on this clinical manifestation. For this purpose, we describe the relationship between orthostatic hypot...

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Bibliographic Details
Main Authors: Alvaro eSanchez-Ferro, Julián eBenito-León, Juan Carlos eGomez-Esteban
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-06-01
Series:Frontiers in Neurology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fneur.2013.00064/full
Description
Summary:Orthostatic hypotension is a common and disabling symptom affecting Parkinson’s disease (PD) patients. We present the effect of the different therapies commonly used to manage Parkinson’s disease on this clinical manifestation. For this purpose, we describe the relationship between orthostatic hypotension and the current treatments employed in PD, such as L-Dopa, dopaminergic agonists, and continuous dopaminergic stimulation therapies. Additionally, we review the therapeutic measures that could be used to ameliorate orthostatic hypotension. There are different approaches to deal with this manifestation, including pharmacological and non-pharmacological treatments, although none of them is specifically aimed for treating orthostatic hypotension in PD.
ISSN:1664-2295