Novel 3-((2-chloroquinolin-3-yl)methylene)indolin-2-one derivatives produce anticancer efficacy in ovarian cancer in vitro

Novel 3-((2-chloroquinolin-3-yl)methylene)indolin-2-one derivatives produce anticancer efficacy in ovarian cancer in vitro

A novel series of 3-((2-chloroquinolin-3-yl)methylene)indolin-2-ones were synthesized, using the ‘molecular hybridization approach’ and evaluated for anticancer efficacy. Eleven 3-((2-chloroquinolin-3-yl)methylene)indolin-2-ones (LM01 to LM11) were synthesized and evaluated for in vitro cytotoxic ef...

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Bibliographic Details
Main Authors: Chandrabose Karthikeyan, Haneen Amawi, Charles R. Ashby, Jr., Vishwa M. Khare, Veronica Jones, N.S. Hari Narayana Moorthy, Piyush Trivedi, Amit K. Tiwari
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:Heliyon
Subjects:
Natural product chemistry
Pharmaceutical science
Pharmaceutical chemistry
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844018350473

Internet

http://www.sciencedirect.com/science/article/pii/S2405844018350473

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