Deciphering Hydrodynamic and Drug-Resistant Behaviors of Metastatic EMT Breast Cancer Cells Moving in a Constricted Microcapillary

Deciphering Hydrodynamic and Drug-Resistant Behaviors of Metastatic EMT Breast Cancer Cells Moving in a Constricted Microcapillary

Epithelial to mesenchymal transition (EMT) induces cell migration, invasion, and drug resistance, and consequently, contributes to cancer metastasis and disease aggressiveness. This study attempted to address crucial biological parameters to correlate EMT and drug-treated cancer cells traversing thr...

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Bibliographic Details
Main Authors: Binita Nath, Anil P. Bidkar, Vikash Kumar, Amaresh Dalal, Mohit Kumar Jolly, Siddhartha S. Ghosh, Gautam Biswas
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Journal of Clinical Medicine
Subjects:
metastasis
constricted microchannel
hydrodynamic parameters
breast cancer cells
epithelial to mesenchymal transition
EMT
mesenchymal to epithelial transition
MET
cell viability
Online Access:https://www.mdpi.com/2077-0383/8/8/1194

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https://www.mdpi.com/2077-0383/8/8/1194

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