Role of water and protein dynamics in proton pumping by respiratory complex I

Abstract Membrane bound respiratory complex I is the key enzyme in the respiratory chains of bacteria and mitochondria, and couples the reduction of quinone to the pumping of protons across the membrane. Recently solved crystal or electron microscopy structures of bacterial and mitochondrial complex...

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Bibliographic Details
Main Authors: Outi Haapanen, Vivek Sharma
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-07930-1