Identification of Antiviral Agents Targeting Hepatitis B Virus Promoter from Extracts of Indonesian Marine Organisms by a Novel Cell-Based Screening Assay

Identification of Antiviral Agents Targeting Hepatitis B Virus Promoter from Extracts of Indonesian Marine Organisms by a Novel Cell-Based Screening Assay

The current treatments of chronic hepatitis B (CHB) face a limited choice of vaccine, antibody and antiviral agents. The development of additional antiviral agents is still needed for improvement of CHB therapy. In this study, we established a screening system in order to identify compounds inhibiti...

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Bibliographic Details
Main Authors: Atsuya Yamashita, Yuusuke Fujimoto, Mayumi Tamaki, Andi Setiawan, Tomohisa Tanaka, Kaori Okuyama-Dobashi, Hirotake Kasai, Koichi Watashi, Takaji Wakita, Masaaki Toyama, Masanori Baba, Nicole J. de Voogd, Shinya Maekawa, Nobuyuki Enomoto, Junichi Tanaka, Kohji Moriishi
Format: Article
Language:English
Published: MDPI AG 2015-11-01
Series:Marine Drugs
Subjects:
marine organism
hepatitis B virus
HBV
HBV core promoter
high-throughput screening
antiviral agent
Online Access:http://www.mdpi.com/1660-3397/13/11/6759

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http://www.mdpi.com/1660-3397/13/11/6759

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