Differential DNA methylation and lymphocyte proportions in a Costa Rican high longevity region

Differential DNA methylation and lymphocyte proportions in a Costa Rican high longevity region

Abstract Background The Nicoya Peninsula in Costa Rica has one of the highest old-age life expectancies in the world, but the underlying biological mechanisms of this longevity are not well understood. As DNA methylation is hypothesized to be a component of biological aging, we focused on this malle...

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Bibliographic Details
Main Authors: Lisa M. McEwen, Alexander M. Morin, Rachel D. Edgar, Julia L. MacIsaac, Meaghan J. Jones, William H. Dow, Luis Rosero-Bixby, Michael S. Kobor, David H. Rehkopf
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Epigenetics & Chromatin
Subjects:
DNA methylation
Epigenetics
Immune aging
Longevity
Biodemography
Epigenetic age
Online Access:http://link.springer.com/article/10.1186/s13072-017-0128-2

Internet

http://link.springer.com/article/10.1186/s13072-017-0128-2

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