Divalent Cation Modulation of Ion Permeation in TMEM16 Proteins

Intracellular divalent cations control the molecular function of <i>transmembrane protein 16</i> (TMEM16) family members. Both anion channels (such as TMEM16A) and phospholipid scramblases (such as TMEM16F) in this family are activated by intracellular Ca<sup>2+</sup> in the...

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Bibliographic Details
Main Authors: Dung M. Nguyen, Hwoi Chan Kwon, Tsung-Yu Chen
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/22/4/2209