Mevalonate Diphosphate Decarboxylase MVD/Erg19 Is Required for Ergosterol Biosynthesis, Growth, Sporulation and Stress Tolerance in Aspergillus oryzae

Mevalonate Diphosphate Decarboxylase MVD/Erg19 Is Required for Ergosterol Biosynthesis, Growth, Sporulation and Stress Tolerance in Aspergillus oryzae

Mevalonate diphosphate decarboxylase (MVD; EC 4.1.1.33) is a key enzyme of the mevalonic acid (MVA) pathway. In fungi, the MVA pathway functions as upstream of ergosterol biosynthesis, and MVD is also known as Erg19. Previously, we have identified Aoerg19 in Aspergillus oryzae using bioinformatic an...

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Bibliographic Details
Main Authors: Yunlong Sun, Yali Niu, Hui Huang, Bin He, Long Ma, Yayi Tu, Van-Tuan Tran, Bin Zeng, Zhihong Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Microbiology
Subjects:
mevalonate diphosphate decarboxylase
Aspergillus oryzae
sporulation
stress tolerance
ergosterol biosynthesis
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.01074/full

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https://www.frontiersin.org/article/10.3389/fmicb.2019.01074/full

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