A role for the unfolded protein response (UPR) in virulence and antifungal susceptibility in Aspergillus fumigatus.

A role for the unfolded protein response (UPR) in virulence and antifungal susceptibility in Aspergillus fumigatus.

Filamentous fungi rely heavily on the secretory pathway, both for the delivery of cell wall components to the hyphal tip and the production and secretion of extracellular hydrolytic enzymes needed to support growth on polymeric substrates. Increased demand on the secretory system exerts stress on th...

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Bibliographic Details
Main Authors: Daryl L Richie, Lukas Hartl, Vishukumar Aimanianda, Michael S Winters, Kevin K Fuller, Michael D Miley, Stephanie White, Jason W McCarthy, Jean-Paul Latgé, Marta Feldmesser, Judith C Rhodes, David S Askew
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2606855?pdf=render

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http://europepmc.org/articles/PMC2606855?pdf=render

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