DNA Copy Number Analysis in Gastrointestinal Stromal Tumors Using Gene Expression Microarrays

DNA Copy Number Analysis in Gastrointestinal Stromal Tumors Using Gene Expression Microarrays

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We report a method, Expression-Microarray Copy Number Analysis (ECNA) for the detection of copy number changes using Affymetrix Human Genome U133 Plus 2.0 arrays, starting with as little as 5 ng input genomic DNA. An analytical approach was developed using DNA isolated from cell lines containing var...

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Bibliographic Details
Main Authors: Raji Pillai, Garrett Miyada, Earl Hubbell, Robert G. Maki, Margaret A. Leversha, Yaron Turpaz, Manqiu Cao, Guoliang Leon Xing, Kai Wu, Cristina R. Antonescu
Format: Article
Language:English
Published: SAGE Publishing 2008-01-01
Series:Cancer Informatics
Subjects:
copy number change
gene expression
array-based comparative genomic hybridization
whole genome amplification
GIST
sarcoma
Online Access:http://la-press.com/article.php?article_id=662

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http://la-press.com/article.php?article_id=662

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