LINT, a novel dL(3)mbt-containing complex, represses malignant brain tumour signature genes.

LINT, a novel dL(3)mbt-containing complex, represses malignant brain tumour signature genes.

Mutations in the l(3)mbt tumour suppressor result in overproliferation of Drosophila larval brains. Recently, the derepression of different gene classes in l(3)mbt mutants was shown to be causal for transformation. However, the molecular mechanisms of dL(3)mbt-mediated gene repression are not unders...

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Bibliographic Details
Main Authors: Karin Meier, Eve-Lyne Mathieu, Florian Finkernagel, L Maximilian Reuter, Maren Scharfe, Gunther Doehlemann, Michael Jarek, Alexander Brehm
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3342951?pdf=render

Internet

http://europepmc.org/articles/PMC3342951?pdf=render

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