The Adhesion G Protein-Coupled Receptor GPR56/ADGRG1 Is an Inhibitory Receptor on Human NK Cells

Natural killer (NK) cells possess potent cytotoxic mechanisms that need to be tightly controlled. Here, we explored the regulation and function of GPR56/ADGRG1, an adhesion G protein-coupled receptor implicated in developmental processes and expressed distinctively in mature NK cells. Expression of...

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Bibliographic Details
Main Authors:	Gin-Wen Chang, Cheng-Chih Hsiao, Yen-Ming Peng, Felipe A. Vieira Braga, Natasja A.M. Kragten, Ester B.M. Remmerswaal, Martijn D.B. van de Garde, Rachel Straussberg, Gabriele M. König, Evi Kostenis, Vera Knäuper, Linde Meyaard, René A.W. van Lier, Klaas P.J.M. van Gisbergen, Hsi-Hsien Lin, Jörg Hamann
Format:	Article
Language:	English
Published:	Elsevier 2016-05-01
Series:	Cell Reports
Subjects:	adhesion GPCRs cytotoxicity immune regulation NK cells transcription factor
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211124716304806

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http://www.sciencedirect.com/science/article/pii/S2211124716304806

The Adhesion G Protein-Coupled Receptor GPR56/ADGRG1 Is an Inhibitory Receptor on Human NK Cells

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