High production of pro-inflammatory cytokines by maternal blood mononuclear cells is associated with reduced maternal malaria but increased cord blood infection

High production of pro-inflammatory cytokines by maternal blood mononuclear cells is associated with reduced maternal malaria but increased cord blood infection

Abstract Background Increased susceptibility to malaria during pregnancy is not completely understood. Cellular immune responses mediate both pathology and immunity but the effector responses involved in these processes have not been fully characterized. Maternal and fetal cytokine and chemokine res...

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Bibliographic Details
Main Authors: Carlota Dobaño, Tamara Berthoud, Maria Nelia Manaca, Augusto Nhabomba, Caterina Guinovart, Ruth Aguilar, Arnoldo Barbosa, Penny Groves, Mauricio H. Rodríguez, Alfons Jimenez, Lazaro M. Quimice, John J. Aponte, Jaume Ordi, Denise L. Doolan, Alfredo Mayor, Pedro L. Alonso
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Malaria Journal
Subjects:
Malaria
P. falciparum
Pregnancy
Cytokines
Immunity
Pathology
Online Access:http://link.springer.com/article/10.1186/s12936-018-2317-2

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http://link.springer.com/article/10.1186/s12936-018-2317-2

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