Looming sensitive cortical regions without V1 input: evidence from a patient with bilateral cortical blindness
Fast and automatic behavioral responses are required to avoid collision with an approaching stimulus. Accordingly, looming stimuli have been found to be highly salient and efficient attractors of attention due to the implication of potential collision and potential threat. Here, we address the quest...
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doaj-60c5c1a68c6249c6b1e36b09b711f0842020-11-24T23:02:11ZengFrontiers Media S.A.Frontiers in Integrative Neuroscience1662-51452015-10-01910.3389/fnint.2015.00051137437Looming sensitive cortical regions without V1 input: evidence from a patient with bilateral cortical blindnessAlexis eHervais-Adelman0Alexis eHervais-Adelman1Lore Billie Legrand2Lore Billie Legrand3Minye eZhan4Marco eTamietto5Marco eTamietto6Beatrice eDe Gelder7Alan J Pegna8Alan J Pegna9Alan J Pegna10University of GenevaUniversity of GenevaGeneva University HospitalsUniversity of GenevaUniversity of MaastrichtUniversity of MaastrichtUniversity of TorinoUniversity of MaastrichtGeneva University HospitalsUniversity of GenevaUniversity of QueenslandFast and automatic behavioral responses are required to avoid collision with an approaching stimulus. Accordingly, looming stimuli have been found to be highly salient and efficient attractors of attention due to the implication of potential collision and potential threat. Here, we address the question of whether looming motion is processed in the absence of any functional primary visual cortex and consequently without awareness. For this, we investigated a patient (TN) suffering from complete, bilateral damage to his primary visual cortex. Using an fMRI paradigm, we measured TN’s brain activation during the presentation of looming, receding, rotating and static point lights, of which he was unaware. When contrasted with other conditions, looming was found to produce bilateral activation of the middle temporal areas, as well as the superior temporal sulcus and inferior parietal lobe. The latter are generally thought to be involved in multisensory processing of motion in extrapersonal space, as well as attentional capture and saliency. No activity was found close to the lesioned V1 area.This demonstrates that looming motion is processed in the absence of awareness through direct subcortical projections to areas involved in multisensory processing of motion and saliency that bypass V1.http://journal.frontiersin.org/Journal/10.3389/fnint.2015.00051/fullHemianopsiaMotion PerceptionVisual CortexVisual FieldsBlindsightfMRI |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Alexis eHervais-Adelman Alexis eHervais-Adelman Lore Billie Legrand Lore Billie Legrand Minye eZhan Marco eTamietto Marco eTamietto Beatrice eDe Gelder Alan J Pegna Alan J Pegna Alan J Pegna |
spellingShingle |
Alexis eHervais-Adelman Alexis eHervais-Adelman Lore Billie Legrand Lore Billie Legrand Minye eZhan Marco eTamietto Marco eTamietto Beatrice eDe Gelder Alan J Pegna Alan J Pegna Alan J Pegna Looming sensitive cortical regions without V1 input: evidence from a patient with bilateral cortical blindness Frontiers in Integrative Neuroscience Hemianopsia Motion Perception Visual Cortex Visual Fields Blindsight fMRI |
author_facet |
Alexis eHervais-Adelman Alexis eHervais-Adelman Lore Billie Legrand Lore Billie Legrand Minye eZhan Marco eTamietto Marco eTamietto Beatrice eDe Gelder Alan J Pegna Alan J Pegna Alan J Pegna |
author_sort |
Alexis eHervais-Adelman |
title |
Looming sensitive cortical regions without V1 input: evidence from a patient with bilateral cortical blindness |
title_short |
Looming sensitive cortical regions without V1 input: evidence from a patient with bilateral cortical blindness |
title_full |
Looming sensitive cortical regions without V1 input: evidence from a patient with bilateral cortical blindness |
title_fullStr |
Looming sensitive cortical regions without V1 input: evidence from a patient with bilateral cortical blindness |
title_full_unstemmed |
Looming sensitive cortical regions without V1 input: evidence from a patient with bilateral cortical blindness |
title_sort |
looming sensitive cortical regions without v1 input: evidence from a patient with bilateral cortical blindness |
publisher |
Frontiers Media S.A. |
series |
Frontiers in Integrative Neuroscience |
issn |
1662-5145 |
publishDate |
2015-10-01 |
description |
Fast and automatic behavioral responses are required to avoid collision with an approaching stimulus. Accordingly, looming stimuli have been found to be highly salient and efficient attractors of attention due to the implication of potential collision and potential threat. Here, we address the question of whether looming motion is processed in the absence of any functional primary visual cortex and consequently without awareness. For this, we investigated a patient (TN) suffering from complete, bilateral damage to his primary visual cortex. Using an fMRI paradigm, we measured TN’s brain activation during the presentation of looming, receding, rotating and static point lights, of which he was unaware. When contrasted with other conditions, looming was found to produce bilateral activation of the middle temporal areas, as well as the superior temporal sulcus and inferior parietal lobe. The latter are generally thought to be involved in multisensory processing of motion in extrapersonal space, as well as attentional capture and saliency. No activity was found close to the lesioned V1 area.This demonstrates that looming motion is processed in the absence of awareness through direct subcortical projections to areas involved in multisensory processing of motion and saliency that bypass V1. |
topic |
Hemianopsia Motion Perception Visual Cortex Visual Fields Blindsight fMRI |
url |
http://journal.frontiersin.org/Journal/10.3389/fnint.2015.00051/full |
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