Ginkgetin aglycone attenuates neuroinflammation and neuronal injury in the rats with ischemic stroke by modulating STAT3/JAK2/SIRT1

Ginkgetin aglycone attenuates neuroinflammation and neuronal injury in the rats with ischemic stroke by modulating STAT3/JAK2/SIRT1

The present investigation evaluates the protective effect of Ginkgetin aglycone (GA) against ischemic stroke-induced neuronal injury. Ischemic stroke was produced by the middle cerebral artery occlusion (MCAO) model and animals were a group that received GA 100 and 200 mg/kg, i.p. five days before t...

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Bibliographic Details
Main Authors: Bing Xu, Xin He, Yi Sui, Xu Wang, Xia Wang, Li Ren, Yun-Xin Zhai
Format: Article
Language:English
Published: Termedia Publishing House 2019-03-01
Series:Folia Neuropathologica
Subjects:
ginkgetin aglycone
ischemic stroke
neuroinflammation
neuronal injury
oxidative stress
Online Access:https://www.termedia.pl/Ginkgetin-aglycone-attenuates-neuroinflammation-and-neuronal-injury-in-the-rats-with-ischemic-stroke-by-modulating-STAT3-JAK2-SIRT1,20,36141,1,1.html

Internet

https://www.termedia.pl/Ginkgetin-aglycone-attenuates-neuroinflammation-and-neuronal-injury-in-the-rats-with-ischemic-stroke-by-modulating-STAT3-JAK2-SIRT1,20,36141,1,1.html

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