The Anti-Inflammatory Effects of Dimethyl Fumarate in Astrocytes Involve Glutathione and Haem Oxygenase-1

The Anti-Inflammatory Effects of Dimethyl Fumarate in Astrocytes Involve Glutathione and Haem Oxygenase-1

DMF (dimethyl fumarate) exerts anti-inflammatory and prometabolic effects in a variety of cell types, and a formulation (BG-12) is being evaluated for monotherapy in multiple sclerosis patients. DMF modifies glutathione (GSH) levels that can induce expression of the anti-inflammatory protein HO-1 (h...

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Bibliographic Details
Main Authors: Shao Xia Lin, Lucia Lisi, Cinzia Dello Russo, Paul E Polak, Anthony Sharp, Guy Weinberg, Sergey Kalinin, Douglas L Feinstein
Format: Article
Language:English
Published: SAGE Publishing 2011-03-01
Series:ASN Neuro
Online Access:https://doi.org/10.1042/AN20100033

Internet

https://doi.org/10.1042/AN20100033

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