Whole blood vs PBMC: compartmental differences in gene expression profiling exemplified in asthma

Abstract Background Blood has proven to be a useful resource for molecular analysis in numerous biomedical studies, with peripheral blood mononuclear cells (PBMCs) and whole blood being the major specimen types. However, comparative analyses between these two major compartments (PBMCs and whole bloo...

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Bibliographic Details
Main Authors: Daniel He, Chen Xi Yang, Basak Sahin, Amrit Singh, Casey P. Shannon, John-Paul Oliveria, Gail M. Gauvreau, Scott J. Tebbutt
Format: Article
Published: BMC 2019-11-01
Series:Allergy, Asthma & Clinical Immunology
Online Access:http://link.springer.com/article/10.1186/s13223-019-0382-x