A Soluble Epoxide Hydrolase Inhibitor, 1-TrifluoromethoxyPhenyl-3-(1-Propionylpiperidin-4-yl) Urea, Ameliorates Experimental Autoimmune Encephalomyelitis

A Soluble Epoxide Hydrolase Inhibitor, 1-TrifluoromethoxyPhenyl-3-(1-Propionylpiperidin-4-yl) Urea, Ameliorates Experimental Autoimmune Encephalomyelitis

Polyunsaturated fatty acids (PUFAs) are essential FAs for human health. Cytochrome P450 oxygenates PUFAs to produce anti-inflammatory and pain-resolving epoxy fatty acids (EpFAs) and other oxylipins whose epoxide ring is opened by the soluble epoxide hydrolase (sEH/<i>Ephx2</i>), resulti...

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Bibliographic Details
Main Authors: Deepa Jonnalagadda, Debin Wan, Jerold Chun, Bruce D. Hammock, Yasuyuki Kihara
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
multiple sclerosis
neurology
neuroinflammation
lipidomics
lipid mediator
bioactive lipids
Online Access:https://www.mdpi.com/1422-0067/22/9/4650

Internet

https://www.mdpi.com/1422-0067/22/9/4650

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